Detalhe da pesquisa
1.
Interactions of hydrolyzed ß-lactams with the L1 metallo-ß-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products.
J Biol Chem
; 299(5): 104606, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36924941
2.
Characterization of 3-[(Carboxymethyl)thio]picolinic Acid: A Novel Inhibitor of Phosphoenolpyruvate Carboxykinase.
Biochemistry
; 58(37): 3918-3926, 2019 09 17.
Artigo
Inglês
| MEDLINE | ID: mdl-31461616
3.
Structural and Kinetic Studies of the Potent Inhibition of Metallo-ß-lactamases by 6-Phosphonomethylpyridine-2-carboxylates.
Biochemistry
; 57(12): 1880-1892, 2018 03 27.
Artigo
Inglês
| MEDLINE | ID: mdl-29485857
4.
Cyclobutanone Mimics of Intermediates in Metallo-ß-Lactamase Catalysis.
Chemistry
; 24(22): 5734-5737, 2018 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-29250863
5.
Arginine-containing peptides as potent inhibitors of VIM-2 metallo-ß-lactamase.
Biochim Biophys Acta
; 1850(11): 2228-38, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26238337
6.
PLCß1a and PLCß1b selective regulation and cyclin D3 modulation reduced by kinamycin F during k562 cell differentiation.
J Cell Physiol
; 230(3): 587-94, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25160985
7.
Experimental estimation of average fidelity of a Clifford gate on a 7-qubit quantum processor.
Phys Rev Lett
; 114(14): 140505, 2015 Apr 10.
Artigo
Inglês
| MEDLINE | ID: mdl-25910102
8.
Assay for drug discovery: Synthesis and testing of nitrocefin analogues for use as ß-lactamase substrates.
Anal Biochem
; 486: 75-7, 2015 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26142222
9.
Evaluation of four microbial Class II fructose 1,6-bisphosphate aldolase enzymes for use as biocatalysts.
Protein Expr Purif
; 80(2): 224-33, 2011 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21763425
10.
Cyclobutanone analogues of beta-lactams revisited: insights into conformational requirements for inhibition of serine- and metallo-beta-lactamases.
J Am Chem Soc
; 132(8): 2558-60, 2010 Mar 03.
Artigo
Inglês
| MEDLINE | ID: mdl-20141132
11.
A biogenetically-inspired synthesis of a ring-D model of kinamycin F: insights into the conformation of ring D.
Org Lett
; 10(3): 381-4, 2008 Feb 07.
Artigo
Inglês
| MEDLINE | ID: mdl-18183994
12.
Cyclobutanone mimics of penicillins: effects of substitution on conformation and hemiketal stability.
J Org Chem
; 73(18): 6970-82, 2008 Sep 19.
Artigo
Inglês
| MEDLINE | ID: mdl-18710291
13.
Assays for beta-lactamase activity and inhibition.
Methods Mol Med
; 142: 239-60, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-18437319
14.
Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F.
Free Radic Biol Med
; 43(8): 1132-44, 2007 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17854709
15.
Total synthesis of isoprekinamycin: structural evidence for enhanced diazonium ion character and growth inhibitory activity toward cancer cells.
Org Lett
; 9(15): 2915-8, 2007 Jul 19.
Artigo
Inglês
| MEDLINE | ID: mdl-17585773
16.
68Zn isotope exchange experiments reveal an unusual kinetic lability of the metal ions in the di-zinc form of IMP-1 metallo-beta-lactamase.
Chem Commun (Camb)
; (5): 532-4, 2006 Feb 07.
Artigo
Inglês
| MEDLINE | ID: mdl-16432573
17.
IMP-1 metallo-beta-lactamase: effect of chelators and assessment of metal requirement by electrospray mass spectrometry.
Biochim Biophys Acta
; 1571(3): 190-200, 2002 Jul 03.
Artigo
Inglês
| MEDLINE | ID: mdl-12090933
18.
Development of metal-chelating inhibitors for the Class II fructose 1,6-bisphosphate (FBP) aldolase.
J Inorg Biochem
; 112: 49-58, 2012 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-22546686
19.
Kinamycin F downregulates cyclin D3 in human leukemia K562 cells.
Chem Biol Interact
; 184(3): 396-402, 2010 Mar 30.
Artigo
Inglês
| MEDLINE | ID: mdl-20079721
20.
High level production of the Magnaporthe grisea fructose 1,6-bisphosphate aldolase enzyme in Escherichia coli using a small volume bench-top fermentor.
Protein Expr Purif
; 51(1): 110-9, 2007 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-16901716